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According to the Saxenda SmPC, treatment should be discontinued if patients have not lost at least 5% of their initial body weight after 12 weeks at the maintenance dose of 3.0 mg/day

The activation of THR is known to improve MASH by controlling fat synthesis, regulating fatty acid oxidation, cholesterol metabolism, mitochondrial function, and reducing inflammation and fibrosis

Although -carotene, retinol, and lutein supplements theoretically have beneficial health impacts, the studys authors found, in a review of the long-term consumption of these nutrients and cancer risk, that it may lead to an increased risk of lung cancer (Satia et al., 2009)

It is not designed for unsupervised or casual use, and long term plans should always involve professional monitoring.The safety of repeated sessions is evaluated based on response, goals, and overall health